Fasting Regulates Hypothalamic Neuropeptide Y, Agouti-Related Peptide, and Proopiomelanocortin in Diabetic Mice Independent of Changes in Leptin or Insulin
نویسندگان
چکیده
منابع مشابه
The effect of Ramadan fasting on serum leptin, neuropeptide Y and insulin in pregnant women
Background :Many pregnant Muslim women choose to fast during Ramadan every year worldwide. This study aimed to examine the effect of Ramadan fasting on serum leptin, neuropeptide Y and insulin in pregnant women and find whether fasting during pregnancy could have a negative effect on the health of mothers and fetuses. Methods : This cross-sectional study was conducted on 39 healthy voluntee...
متن کاملDifferential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice.
Insulin resistance and type 2 diabetes correlate with impaired leptin and insulin signaling. Insulin receptor substrate-2 deficient (IRS2(-/-)) mice are an accepted model for the exploration of alterations in these signaling pathways and their relationship with diabetes; however, disturbances in hypothalamic signaling and the effect on neuropeptides controlling food intake remain unclear. Our a...
متن کاملthe effect of ramadan fasting on serum leptin, neuropeptide y and insulin in pregnant women
background :many pregnant muslim women choose to fast during ramadan every year worldwide. this study aimed to examine the effect of ramadan fasting on serum leptin, neuropeptide y and insulin in pregnant women and find whether fasting during pregnancy could have a negative effect on the health of mothers and fetuses. methods : this cross-sectional study was conducted on 39 healthy volunteer ...
متن کاملDifferential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event.
Stress affects eating behaviour in rodents and humans, suggesting that the regulation of energy balance and the stress response are coupled physiological processes. Neuropeptide Y (NPY) and agouti-related protein (AgRP) are potent food-stimulating neuropeptides that are highly co-localised in arcuate nucleus neurons of the hypothalamus. Recent studies have shown that NPY and AgRP mRNA levels in...
متن کاملAging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression.
To investigate the role of aging on the fasting-induced suppression of leptin gene expression and increase in hypothalamic neuropeptide Y (NPY) gene expression, we fasted or fed ad libitum male F-344xBN rats aged 3, 24, and 31 mo for 2 days. We examined leptin mRNA levels in retroperitoneal, inguinal, and epididymal white adipose tissue (WAT); serum leptin levels; and NPY mRNA levels in the hyp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 1999
ISSN: 0013-7227
DOI: 10.1210/en.140.10.4551